The protein encoded by CDK13 (cyclin dependent kinase 13) is a member of the cyclin-dependent serine/threonine protein kinase family.
Members of this family are well known for their essential roles as master switches in cell cycle control.
The exact function of this protein has not yet been determined, but it may play a role in mRNA processing and may be involved in regulation of hematopoiesis.
Alternatively spliced transcript variants have been described.
CDK13 is a protein coding gene.
Diseases associated with CDK13 include congenital heart defects, dysmorphic facial features, and intellectual developmental disorder and corneal endothelial dystrophy, autosomal recessive.
Among its related pathways are formation of HIV elongation complex in the absence of HIV tat and innate immune system.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity:Recognizes endogenous levels of human CDK13. Species Crossreactivity: mouse
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Hu Mo
Immunogen:Synthetic peptide corresponding to aa650-730 from human CDK13.