The protein encoded by CD70 (CD70 molecule) is a protein coding gene.
Diseases associated with CD70 include acute myocarditis and lymphoproliferative syndrome 2.
Among its related pathways are T cell co-signaling pathway: ligand-receptor interactions and akt signaling.
is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family.
This cytokine is a ligand for TNFRSF27/CD27.
It is a surface antigen on activated, but not on resting, T and B lymphocytes.
It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation.
This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.
CD70 (CD70 molecule) is a protein coding gene.
Diseases associated with CD70 include acute myocarditis and lymphoproliferative syndrome 2.
Among its related pathways are T cell co-signaling pathway: ligand-receptor interactions and akt signaling.
Applications:Suitable for use in Immunohistochemistry (paraffin), ELISA.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (paraffin): 1:50-1:200ELISA: 1:10,000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:30ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity:Recognizes endogenous levels of human CD70 . Species Crossreactivity: mouse
Isotype:IgG
Calc Applications Abbrev:E IHC
Calc Crossreactivity:Hu Mo
Immunogen:Synthetic peptide corresponding to aa150-193 from human CD70.