CD109 encodes a glycosyl phosphatidylinositol (GPI)-linked glycoprotein that localizes to the surface of platelets, activated T-cells, and endothelial cells.
The protein binds to and negatively regulates signalling by transforming growth factor beta (TGF-beta).
Multiple transcript variants encoding different isoforms have been found for CD109.
CD109 (CD109 molecule) is a protein coding gene.
Diseases associated with CD109 include fetal and neonatal alloimmune Thrombocytopenia and epithelioid sarcoma.
Among its related pathways are response to elevated platelet cytosolic Ca2+ and metabolism of proteins.
Applications:Suitable for use in Immunohistochemistry (paraffin), ELISA.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (paraffin): 1:50-1:200ELISA: 1:10,000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：30ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human CD109.
Isotype：IgG
Calc Applications Abbrev：E IHC
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to aa751-800 from human CD109.
