84-5427-59　［取扱停止］CD101 30ul　534208

特徴

• CD101 (CD101 Molecule) is a Protein Coding gene.
• Diseases associated with CD101 include langerhans-cell histiocytosis and histiocytosis.
• Among its related pathways are Innate Lymphoid Cell Differentiation Pathways.
• Gene Ontology (GO) annotations related to this gene include hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides.
• An important paralog of this gene is PTGFRN.
• Plays a role as inhibitor of T-cells proliferation induced by CD3.
• Inhibits expression of IL2RA on activated T-cells and secretion of IL2.
• Inhibits tyrosine kinases that are required for IL2 production and cellular proliferation.
• Inhibits phospholipase C-gamma-1/PLCG1 phosphorylation and subsequent CD3-induced changes in intracellular free calcium.
• Prevents nuclear translocation of nuclear factor of activated T-cell to the nucleus.
• Plays a role in the inhibition of T-cell proliferation via IL10 secretion by cutaneous dendritic cells.
• May be a marker of CD4(+) CD56(+) leukemic tumor cells.
• Applications:Suitable for use in Western Blot and ELISA.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:10,000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.