The protein encoded by CCR9 is a member of the beta chemokine receptor family.
It is predicted to be a seven transmembrane protein similar to G protein-coupled receptors.
Chemokines and their receptors are key regulators of the thymocytes migration and maturation in normal and inflammation conditions.
The specific ligand of this receptor is CCL25.
It has been found that CCR9 is differentially expressed by T lymphocytes of small intestine and colon, suggested a role in the thymocytes recruitment and development that may permit functional specialization of immune responses in different segment of the gastrointestinal tract.
CCR9 is mapped to the chemokine receptor gene cluster region.
Two alternatively spliced transcript variants have been described.
Multiple transcript variants encoding different isoforms have been found for CCR9.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:10,000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：30ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human CCR9. Species Crossreactivity: mouse
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu Mo
Immunogen：Synthetic peptide corresponding to aa140-220 from human CCR9.
