LGALS3 encodes a member of the galectin family of carbohydrate binding proteins.
Members of this protein family have an affinity for beta-galactosides.
The galectin-3 is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain.
This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands.
This protein localizes to the extracellular matrix, the cytoplasm and the nucleus.
This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation.
The protein exhibits antimicrobial activity against bacteria and fungi.
Alternate splicing results in multiple transcript variants.
Applications:Suitable for use in Western Blot, Immunohistochemistry, and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry (paraffin): 1:100-1:300ELISA: 1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human CBP 35.
Isotype：IgG
Calc Applications Abbrev：E IHC WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to human CBP 35 at C-terminal.
