The preproprotein encoded by CACNA2D1 (calcium voltage-gated channel auxiliary subunit alpha2delta 1) is cleaved into multiple chains that comprise the alpha-2 and delta subunits of the voltage-dependent calcium channel complex.
Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization.
Mutations in CACNA2D1 can cause cardiac deficiencies, including Brugada syndrome and short QT syndrome.
Alternate splicing results in multiple transcript variants, some of which may lack the delta subunit portion.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：30ul
Host：rabbit
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes CaV alpha2 beta1. Species Crossreactivity: rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Rt
Immunogen：Synthetic peptide corresponding to CaV alpha2 delta1.
