CSNK2B encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication.
The enzyme (casein kinase 2 beta) is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme.
The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions.
The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus.
Two transcript variants encoding different isoforms have been found for CSNK2B.
Applications:Suitable for use in Western Blot, Immunohistochemistry, and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry (paraffin): 1:100-1:300ELISA: 1:5000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:30ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Specificity:Recognizes endogenous levels of human Casein Kinase IIbeta. Species Crossreactivity: mouse, rat
Isotype:IgG
Calc Applications Abbrev:E IHC WB
Calc Crossreactivity:Hu Mo Rt
Immunogen:Synthetic peptide corresponding to human Casein Kinase IIbeta around the non-phosphorylation site of S209.