CACNA1G (calcium voltage-gated channel subunit alpha1 G) is a protein coding gene.
Diseases associated with CACNA1G include spinocerebellar ataxia 42 and central pain syndrome.
Among its related pathways are arrhythmogenic right ventricular cardiomyopathy (ARVC) and calcium signaling pathway.
Voltage-sensitive calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division, and cell death.
CACNA1G encodes a T-type, low-voltage activated calcium channel.
The T-type channels generate currents that are both transient, owing to fast inactivation, and tiny, owing to small conductance.
T-type channels are thought to be involved in pacemaker activity, low-threshold calcium spikes, neuronal oscillations and resonance, and rebound burst firing.
Many alternatively spliced transcript variants encoding different isoforms have been described for CACNA1G.
Applications:Suitable for use in Immunohistochemistry (paraffin).
Other applications not tested.
Recommended Dilution:Immunohistochemistry (paraffin): 1:50-1:300Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：30ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human CAC1G. Species Crossreactivity: rat
Isotype：IgG
Calc Applications Abbrev：IHC
Calc Crossreactivity：Hu Rt
Immunogen：Synthetic peptide corresponding to aa360-440 from human CAC1G.
