C1qL2 (complement C1q-like protein 2), also known as CTRP10 or C1QTNF10, is a 287aa secreted protein that contains one C1q domain and one collagen-like domain.
C1qL2 belongs to a large family of multimeric proteins with a signature globular domain homologous to C1QA.
These proteins also share structural homology with TNF family members.
The gene that encodes C1qL2 consists of approximately 2653 bases and maps to human chromosome 2q14.2.
Consisting of 237 million bases, chromosome 2 encodes over 1,400 genes and makes up approximately 8% of the human genome.
A number of genetic diseases are linked to genes on chromosome 2.
Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene.
The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8.
An extremely rare recessive genetic disorder, Alström syndrome, is due to mutations in the ALMS1 gene.
Applications:Suitable for use in Western Blot, Immunohistochemistry, and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry (paraffin): 1:100-1:300ELISA: 1:10,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human C1qL2. Species Crossreactivity: mouse
Isotype：IgG
Calc Applications Abbrev：E IHC WB
Calc Crossreactivity：Hu Mo
Immunogen：Synthetic peptide corresponding to aa200-280 of human C1qL2 at C-terminal.
