BMP1 encodes a protein that is capable of inducing formation of cartilage in vivo.
Although other bone morphogenetic proteins are members of the TGF-beta superfamily, BMP1 encodes a protein that is not closely related to other known growth factors.
BMP1 is expressed as alternatively spliced variants that share an N-terminal protease domain but differ in their C-terminal region.
BMP1 (bone morphogenetic protein 1) is a protein coding gene.
Diseases associated with BMP1 include osteogenesis imperfecta, type Xiii and Bmp1-related osteogenesis imperfecta.
Among its related pathways are p70S6K signaling and SMAD signaling network.
Applications:Suitable for use in Immunohistochemistry (paraffin), .
Other applications not tested.
Recommended Dilution:Immunohistochemistry (paraffin): 1:50-1:200ELISA: 1:10,000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：30ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human BMP-1. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：E IHC
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to aa131-180 from human BMP-1.
