SAG (S-antigen visual arrestin) is a protein coding gene.
Diseases associated with SAG include Oguchi disease-1 and retinitis pigmentosa 47.
Among its related pathways are phototransduction and visual cycle in retinal rods.
S-arrestin, also known as S-antigen, is a major soluble photoreceptor protein that is involved in desensitization of the photoactivated transduction cascade.
It is expressed in the retina and the pineal gland and inhibits coupling of rhodopsin to transducin in vitro.
Additionally, S-arrestin is highly antigenic, and is capable of inducing experimental autoimmune uveoretinitis.
Mutations in SAG have been associated with Oguchi disease, a rare autosomal recessive form of night blindness.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：30ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human ARRS.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to aa210-290 from human ARRS.
