The specific function of ACTR3 has not yet been determined; however, the protein (ARP3 actin related protein 3 homolog) it encodes is known to be a major constituent of the ARP2/3 complex.
This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion.
Three transcript variants encoding two different isoforms have been found for ACTR3.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:40,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Specificity:Recognizes endogenous levels of human Arp3. Species Crossreactivity: mouse, rat
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Hu Mo Rt
Immunogen:Synthetic peptide corresponding to aa340-420 of human Arp3 at C-terminal.