AURKB (aurora kinase B) encodes a member of the aurora kinase subfamily of serine/threonine kinases.
The genes encoding the other two members of this subfamily are located on chromosomes 19 and 20.
These kinases participate in the regulation of alignment and segregation of chromosomes during mitosis and meiosis through association with microtubules.
A pseudogene of AURKB is located on chromosome 8.
Alternatively spliced transcript variants have been found for AURKB.
Applications:Suitable for use in Immunohistochemistry and ELISA.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (paraffin): 1:100-1:300ELISA: 1:10,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：30ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human ARK-2/3 only when phosphorylated at T236/202. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：E IHC
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to human ARK-2/3 around the phosphorylation site of T236/202.
