SLC25A12 encodes a calcium-binding mitochondrial carrier protein.
The encoded protein (solute carrier family 25 member 12) localizes to the mitochondria and is involved in the exchange of aspartate for glutamate across the inner mitochondrial membrane.
Polymorphisms in this gene may be associated with autism, and mutations in SLC25A12 may also be a cause of global cerebral hypomyelination.
Alternatively spliced transcript variants have been observed for SLC25A12.
Applications:Suitable for use in Western Blot, Immunohistochemistry, and ELISA.
Other applications not tested.
Recommended Dilution:Western blot: 1:500-1:2000Immunohistochemistry (paraffin): 1:100-1:300ELISA: 1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human ARALAR.
Isotype：IgG
Calc Applications Abbrev：E IHC WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to aa360-440 of human ARALAR.
