Transcription factor AP-2 alpha encoded by TFAP2A is a transcription factor that binds the consensus sequence 5'-GCCNNNGGC-3'.
The encoded protein functions as either a homodimer or as a heterodimer with similar family members.
This protein activates the transcription of some genes while inhibiting the transcription of others.
Defects in this gene are a cause of branchiooculofacial syndrome (BOFS).
Three transcript variants encoding different isoforms have been found for TFAP2A.
Applications:Suitable for use in Western Blot, Immunohistochemistry, and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry (paraffin): 1:100-1:300ELISA: 1:10,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：30ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human AP-2alpha/beta. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：E IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to aa360-440 of human AP-2 alpha/beta at C-terminal.
