ANXA1 encodes a membrane-localized protein that binds phospholipids.
This protein ANXA1 inhibits phospholipase A2 and has anti-inflammatory activity.
Loss of function or expression of this gene has been detected in multiple tumors.
ANXA1 (Annexin A1) is a Protein Coding gene.
Diseases associated with ANXA1 include Hairy Cell Leukemia and Brain Edema.
Among its related pathways are Prostaglandin Synthesis and Regulation and Signaling by GPCR.
Applications:Suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence, and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry (paraffin): 1:50-1:200Immunofluorescence: 1:200-1:500ELISA: 1:10,000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity:Recognizes endogenous levels of human Annexin I at ~38kD.
Isotype:IgG
Calc Applications Abbrev:E IF IHC WB
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide corresponding to aa130-180 of human Annexin I.