ADAMTS1 encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family.
Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif.
Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains.
ADAM metallopeptidase with thrombospondin type 1 motif 1 encoded by ADAMTS1 contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity.
The expression of ADAMTS1 may be associated with various inflammatory processes as well as development of cancer cachexia.
ADAMTS1 is likely to be necessary for normal growth, fertility, and organ morphology and function.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:5000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：30ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human ADAMTS-1.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to aa160-240 of human ADAMTS-1.
