84-5399-45　［取扱停止］AChR alpha3 100ul　532703

特徴

• CHRNA3 encodes a member of the nicotinic acetylcholine receptor family of proteins.
• Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits.
• CHRNA3 encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues.
• The encoded protein (cholinergic receptor nicotinic alpha 3 subunit) is a ligand-gated ion channel that likely plays a role in neurotransmission.
• Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer.
• Alternatively spliced transcript variants have been described.
• Applications:Suitable for use in Western Blot and ELISA.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:10,000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.