CHRNB3 (cholinergic receptor nicotinic beta 3 subunit) is a protein coding gene.
Diseases associated with CHRNB3 include Duane retraction syndrome and autosomal dominant nocturnal frontal lobe epilepsy.
Among its related pathways are nanog in mammalian ESC pluripotency and acetylcholine binding and downstream events.
The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses.
The nAChRs are (hetero) pentamers composed of homologous subunits.
The subunits that make up the muscle and neuronal forms of nAChRs are encoded by separate genes and have different primary structure.
There are several subtypes of neuronal nAChRs that vary based on which homologous subunits are arranged around the central channel.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human ACHB3. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to aa160-240 from human ACHB3.
