This gene encodes one of the two B-type lamin proteins and is a component of the nuclear lamina.
A duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD).
Alternative splicing results in multiple transcript variants.
Applications:Suitable for use in Western Blot, Immunofluorescence and Immunoprecipitation.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunofluorescence: 1:50-1:200Immunoprecipitation: 1:50-1:200Optimal dilutions to be determined by the researcher.