84-5325-77 UNC5C 100ul 529498
特徴
- Receptor for netrin required for axon guidance.
- Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.
- Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion.
- Also involved in corticospinal tract axon guidances independently of DCC.
- It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand.
- Applications:Suitable for use in Western Blot and ELISA.
- Other applications not tested.
- Recommended Dilution:Western Blot: 1:500-1:2000ELISA (peptide): 1:20,000-1:40,000Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size:100ul
- Host:rabbit
- Grade:Affinity Purified
- Purity:Purified by immunoaffinity chromatography.
- Form:Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Specificity:Recognizes endogenous levels of total UNC5C. Species Crossreactivity: Human, mouse and rat
- Isotype:IgG
- Calc Applications Abbrev:E WB
- Calc Crossreactivity:Hu Mo Rt
- Immunogen:Synthetic peptide corresponding to UNC5C at C-terminal. Species sequence homology: Porcine (100%), Zebrafish (82%), Bovine (100%), Equine (100%), Sheep (100%), Rabbit (100%), Canine (100%), Chicken (91%)
- Swiss Prot Number:O95185
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