84-5311-99　SYNGAP1 100ul　528786

特徴

• Major constituent of the PSD essential for postsynaptic signaling.
• Inhibitory regulator of the Ras-cAMP pathway.
• Member of the NMDAR signaling complex in excitatory synapses, it may play a role in NMDAR-dependent control of AMPAR potentiation, AMPAR membrane trafficking and synaptic plasticity.
• Regulates AMPAR-mediated miniature excitatory postsynaptic currents.
• Exhibits dual GTPase-activating specificity for Ras and Rap.
• May be involved in certain forms of brain injury, leading to long-term learning and memory deficits (By similarity).
• Applications:Suitable for use in Western Blot and ELISA.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:1000-1:3000, incubate membrane with diluted primary antibody in TBS, 5% milk, 0.1% Tween 20 at 4°C with gentle shaking, overnight
• ELISA (peptide): 1:20,000-1:40,000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.