84-5307-01 SOX17 100ul 528519
特徴
- Acts as transcription regulator that binds target promoter DNA and bends the DNA.
- Binds to the sequences 5'-AACAAT-'3 or 5'-AACAAAG-3'.
- Modulates transcriptional regulation via WNT3A.
- Inhibits Wnt signaling.
- Promotes degradation of activated CTNNB1.
- Plays a key role in the regulation of embryonic development.
- Required for normal looping of the embryonic heart tube.
- Required for normal development of the definitive gut endoderm.
- Probable transcriptional activator in the premeiotic germ cells (By similarity).
- Applications:Suitable for use in Western Blot and ELISA.
- Other applications not tested.
- Recommended Dilution:Western Blot: 1:1000-1:3000, incubate membrane with diluted antibody in TBS, 5% milk, 0.1% Tween20 at 4°C with gentle shaking, overnight
- ELISA (peptide): 1:20,000-1:40,000Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：100ul
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by immunoaffinity chromatography.
- Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Specificity：Recognizes endogenous levels of total human SOX17. Species Crossreactivity: mouse
- Isotype：IgG
- Calc Applications Abbrev：E WB
- Calc Crossreactivity：Hu Mo
- Immunogen：Synthetic peptide corresponding to human SOX17. Species sequence homology: porcine (100%), bovine (100%), sheep (100%), canine (100%)
- Swiss Prot Number：Q9H6I2
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