Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.
Necessary for recycling of internalized ADRB2.
Was first known to play a role in the regulation of the activity and subcellular location of SLC9A3.
Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3.
May enhance Wnt signaling.
May participate in HTR4 targeting to microvilli (By similarity).
Involved in the regulation of phosphate reabsorption in the renal proximal tubules.
Involved in sperm capacitation.
May participate in the regulation of the chloride and bicarbonate homeostasis in spermatozoa.
Applications:Suitable for use in Western Blot, Immunohistochemistry and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:1000-3000Immunohistochemistry: 1:200ELISA (peptide): 1:20,000-1:40,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography from serum.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of total human SLC9A3R1. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：E IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to human SLC9A3R1. Species sequence homology: bovine (100%), equine (100%), sheep (100%), rabbit (92%), canine (100%)
