84-5290-52　REG3G 100ul　527670

特徴

• The regeneration (REG) family consists of secretory proteins involved in liver, pancreatic, gastric and intestinal cell proliferation or differentiation.
• Members of the REG family are divided into four subclasses, designated types I, II, III and IV, all of which share a common gene structure containing five introns and six exons.
• Members of the Reg family have been implicated in the regulation of cell growth, tumorigenesis and the progression of cancer.
• Reg lll (regenerating islet-derived 3 gamma), also known as pancreatitis-associated protein 1B, PAP1B, or UNQ429, is a 175aa secreted protein that is expressed almost exclusively in pancreas, with low levels of expression in testis.
• Reg lll functions as an antimicrobial protein involved in controlling bacterial proliferation and may be induced during acute pancreatitis.
• The gene encoding Reg lll maps to human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome.
• Applications:Suitable for use in Western Blot, Immunohistochemistry and ELISA.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000, incubate membrane with diluted primary antibody in TBS, 5% milk, 0.1% Tween 20 at 4°C with gentle shaking, overnight
• Immunohistochemistry: 1:50-1:200ELISA (peptide): 1:20,000-1:40,000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.