84-5276-28 PHLA2 100ul 526922
特徴
- Location-regulated scaffold connecting MEK to RAF.
- Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling.
- Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production.
- Belongs to the protein kinase superfamily.
- TKL Ser/Thr protein kinase family.
- Interacts with MAP2K1, MAP3K8, MAPK, RAS and RAF.
- 2 isoforms of the human protein are produced by alternative splicing.
- Applications:Suitable for use in Western Blot, Immunohistochemistry and ELISA.
- Other applications not tested.
- Recommended Dilution:Immunohistochemistry: 1:50-1:200Western Blot: 1:500-1:2000, incubate membrane with diluted primary antibody in TBS, 5% milk, 0.1% Tween 20 at 4°C with gentle shaking, overnight
- ELISA (peptide): 1:20,000-1:40,000Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：100ul
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by immunoaffinity chromatography.
- Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Specificity：Recognizes endogenous levels of human PHLA2.
- Isotype：IgG
- Calc Applications Abbrev：E IHC WB
- Calc Crossreactivity：Hu
- Immunogen：Synthetic peptide corresponding to human PHLA2.
- Swiss Prot Number：Q53GA4
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