Scaffolding protein that is part of a multiprotein signaling complex.
Promotes phosphorylation of Raf family members and activation of downstream MAP kinases.
Promotes activation of MAPK1 and/or MAPK3, both in response to EGF and to cAMP.
Does not have kinase activity by itself.
Applications:Suitable for use in Western Blot, Immunohistochemistry and ELISA.
Other applications not tested.
Recommended Dilutions:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200ELISA (peptide): 1:20,000-1:40,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human KSR1 only when phosphorylated at Ser392/406. Species Crossreactivity: mouse
Isotype：IgG
Calc Applications Abbrev：E IHC WB
Calc Crossreactivity：Hu Mo
Immunogen：Synthesized peptide derived from human KSR1 around the phosphorylation site of Ser392/406. Species sequence homology: Porcine (100%), Bovine (100%), Rabbit (100%), Canine (100%), Chicken (92%)
