Scaffolding protein that is part of a multiprotein signaling complex.
Promotes phosphorylation of Raf family members and activation of downstream MAP kinases.
Promotes activation of MAPK1 and/or MAPK3, both in response to EGF and to cAMP.
Does not have kinase activity by itself.
Applications:Suitable for use in Western Blot, Immunofluorescence/Immunocytochemistry and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:1000-3000Immunofluorescence (IF-IC): 1:100-1:500ELISA (peptide): 1:20,000-1:40,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity:Recognizes endogenous levels of total human KSR1. Species Crossreactivity: mouse and rat
Isotype:IgG
Calc Applications Abbrev:E IC IF WB
Calc Crossreactivity:Hu Mo Rt
Immunogen:Synthetic peptide corresponding to human KSR1. Species sequence homology: porcine (83%), bovine (100%), rabbit (83%), canine (100%)