84-5209-10　GOLPH3 200ul　523414

特徴

• Phosphatidylinositol-4-phosphate-binding protein that links Golgi membranes to the cytoskeleton and may participate in the tensile force required for vesicle budding from the Golgi.
• Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus.
• May also bind to the coatomer to regulate Golgi membrane trafficking.
• May play a role in anterograde transport from the Golgi to the plasma membrane and regulate secretion.
• Has also been involved in the control of the localization of Golgi enzymes through interaction with their cytoplasmic part.
• May play an indirect role in cell migration.
• Has also been involved in the modulation of mTOR signaling.
• May also be involved in the regulation of mitochondrial lipids biosynthesis.
• Applications:Suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence/Immunocytochemistry and ELISA.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000, incubate membrane with diluted antibody in TBS, 5% milk, 0.1% Tween20 at 4°C with gentle shaking, overnight
• Immunohistochemistry: 1:50-1:200Immunofluorescence (IF-IC): 1:100-1:500ELISA (peptide): 1:20,000-1:40,000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.