84-5192-73　EGF 200ul　522529

特徴

• This gene encodes a member of the epidermal growth factor superfamily.
• The encoded protein is synthesized as a large precursor molecule that is proteolytically cleaved to generate the 53aa epidermal growth factor peptide.
• This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types.
• This protein acts by binding the high affinity cell surface receptor, epidermal growth factor receptor.
• Defects in this gene are the cause of hypomagnesemia type 4.
• Dysregulation of this gene has been associated with the growth and progression of certain cancers.
• Alternate splicing results in multiple transcript variants.
• Applications:Suitable for use in Western Blot, Immunohistochemistry and ELISA.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000, incubate membrane with diluted primary antibody in TBS, 5% milk, 0.1% Tween 20 at 4°C with gentle shaking, overnight
• Immunohistochemistry: 1:50-1:100ELISA (peptide): 1:20,000-1:40,000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.