Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P).
S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues.
Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins (By similarity).
May play a regulatoryrole in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells.
Applications:Suitable for use in Western Blot, Immunohistochemistry, and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200ELISA (peptide): 1:20,000-1:40,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of total human EDG8. Species Crossreactivity: mouse
Isotype：IgG
Calc Applications Abbrev：E IHC WB
Calc Crossreactivity：Hu Mo
Immunogen：Synthetic peptide corresponding to human EDG8 at C-terminal. Species sequence homology: porcine (100%), bovine (100%)
