Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4.
Can mediate cell survival as well as cell death of neural cells.
Homodimer; disulfide-linked.
Interacts with p75NTR- associated cell death executor.
Interacts with TRAF2, TRAF4, TRAF6, PTPN13 and RANBP9.
Interacts through TRAF6 with SQSTM1 which bridges NGFR to NTRK1.
Interacts with BEX1 and NGFRAP1/BEX3.
Interacts with KIDINS220 and NTRK1.
Applications:Suitable for use in Western Blot, Immunofluorescence/Immunocytochemistry and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:3000Immunofluorescence/Immunocytochemistry (IF-IC): 1:100-1:500ELISA (peptide): 1:20,000-1:40,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography from serum.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of total human CD271. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：E IC IF WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to human CD271.
