TRAPPC5 (trafficking protein particle complex 5), also known as TRS31, is a 181aa protein belonging to the TRAPP (transport protein particle) small subunits family and the BET3 subfamily.
Encoded by a gene that maps to human chromosome 19p13.2, TRAPPC5 is part of the multisubunit TRAPP tethering complex,which acts as a GTP exchange factor.
Evolutionarily conserved, TRAPPC5 plays a role in protein binding,vesicle-mediated transport and nucleotide exchange stimulation.
TRAPPC5 also performs guanine nucleotide exchanger factor (GEF) functions both in vitro and in vivo.Localizing to the Golgi apparatus, TRAPPC5 is essential for endoplasmic reticulum(ER)-to-Golgi and intra-Golgi vesicle trafficking in yeast, aswell as additional transport events in mammals,such as post--Golgi trafficking.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.3, 0.05% sodium azide.
Specificity：Recognizes endogenous levels of human TRAPPC5 protein. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to aa68-113 of human TRAPPC5.
