SUN2 (sad1/unc-84 protein-like 2), also known as UNC84B (unc-84 homolog B), FRIGG, KIAA0668 or RAB5IP, is a 717aa single-pass membrane protein that contains one SUN domain and localizes to the membrane of both the nucleus and the endosome.
Widely expressed in a variety of tissues, including lung, muscle and heart, SUN2 interacts with Rab 5A and may play a role in homotypic endosome fusion.
The gene encoding SUN2 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome.
Applications:Suitable for use in Immunofluorescence, Flow Cytometry, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:Immunofluorescence: 1:50-1:100Flow Cytometry: 1:50-1:100Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Immunocytochemistry: 1:50-1:100Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in Tris, pH 7.4, 1% BSA, 0.05% sodium azide, 40% glycerol
Specificity：Recognizes endogenous levels of human SUN2 and does not cross-react with related proteins. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：FC IC IF IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Recombinant protein corresponding to aa500-700 of human SUN2.
