STAMP2 (SixTransMembrane protein of prostate 2), also known as STEAP4 (STEAP family member 4), TIARP or TNFAIP9, is a 459aa multi-pass membrane protein that localizes to the golgi apparatus and contains one ferric oxidoreductase domain.
Expressed ubiquitously with highest expression in lung, prostate, placenta and heart, STAMP2 functions as a metalloreductase that uses FAD as a cofactor to reduce both Fe3+ and Cu2+ to Fe2+ and Cu1+, respectively.
Multiple isoforms of STAMP2 exist due to alternative splicing events.
The gene encoding STAMP2 maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome.
Defects in some of the genes localized to chromosome 7 have been linked to Osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.3, 0.05% sodium azide.
Specificity：Recognizes endogenous levels of human STEAP4 protein. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to aa195-240 of human STEAP4.
