84-5133-22 [取扱停止]p68 RNA Helicase, phosphorylated (Y593) 50ul 505948
特徴
- p68 RNA Helicase is a nuclear protein that exhibits RNA-dependent ATPase activity.
- Phosphorylation by protein kinase C inhibits p68 RNA Helicase activity.
- p68 RNA Helicase appears to play a role in organ differentiation during development.
- Furthermore, p68 RNA Helicase is expressed in early neural development and in various mesodermal tissues in a number of different chordate embryos.
- At the cellular level, the expression levels of p68 RNA Helicase increase in serum-induced quiescent cell lines.
- p68 RNA Helicase may function as a coactivator for estrogen receptor α.
- Additionally, p68 RNA Helicase associates with transcriptional coactivators CBP and p300.
- p68 RNA Helicase localizes to the nucleus under normal conditions.
- During late telophase, p68 RNA Helicase and fibrillarin co-localize to nascent nucleoli.
- p68 RNA Helicase may function as a heterodimer with p72 RNA Helicase.
- Applications:Suitable for use in Western Blot.
- Other applications not tested.
- Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size:50ul
- Host:rabbit
- Source Antibody:human
- Grade:Affinity Purified
- Purity:Purified by immunoaffinity chromatography.
- Form:Supplied as a liquid in PBS, pH 7.2, 0.05% sodium azide.
- Specificity:Recognizes endogenous levels of human p68 RNA Helicase protein only when phosphorylated at Tyr593. Species Crossreactivity: mouse and rat
- Isotype:IgG
- Calc Applications Abbrev:WB
- Calc Crossreactivity:Hu Mo Rt
- Immunogen:Synthetic peptide derived from human p68 RNA Helicase around the phosphorylation site of Y593.
- Shelf Life:6months
- Swiss Prot Number:P17844
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