LMO3 (LIM domain only 3), also known as RBTN3 (Rhombotin-3), RBTNL2 or RHOM3, is a 145aa protein that contains two LIM zinc-binding domains and may be involved in transcriptional regulation events in tissues throughout the body.
Aberrant expression of LMO3 is associated with the genesis and progression of human neuroblastoma, suggesting a role for LMO3 in oncogenesis.
The gene encoding LMO3 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome.
Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and Trisomy 12p, which causes facial developmental defects and seizure disorders.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.3, 0.05% sodium azide.
Specificity：Recognizes endogenous levels of human LMO3 protein. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to aa101-145 of human LMO3.
