IPPK (Inositol-pentakisphosphate 2-kinase) is a 491aa gene product that belongs to the IPK1 type 2 family.
IPPK expresses the conserved EXKPK motif which is found in both inositol-pentakisphosphate 2-kinase families 1 and 2.
The primary function of IPPK has been found to be the ATP dependent phosphorylation of Ins (1,3,4,5,6)P5 at position 2 to form Ins (1,2,3,4,5,6)P6 (InsP6 or phytate).
In plants, phytic acid (myo-inositol hexakisphosphate, InsP6) is an important molecule for phosphate storage and signaling.
Mutation of the InsP6 gene can cause plants to be of greater susceptibility to many viral pathogens.
In mice, InsP6 is believed to influence endocytosis and mRNA export.
Homozygous mutations of the IPPK gene will prevent yolk sac development, indicating the importance of this gene product.
IPPK is a ubiquitously expressed protein with highest expression found in heart, testis and brain.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.3, 0.05% sodium azide.
Specificity：Recognizes endogenous levels of human IPPK protein. Species Crossreactivity: mouse
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo
Immunogen：Synthetic peptide corresponding to aa13-57 of human IPPK.
