OX2 (CD200, MOX2), a member of the immunoglobulin superfamily (IgSF), is a 248-residue cell surface glycoprotein that is expressed in lymphoid cells, neurons and endothelium.
OX2 receptor (OX2R) is a membrane protein with up to 70% of its weight derived from N-linked glycosylation, and it is primarily expressed in lymphoid and neuronal tissue.
Phylogenetic analysis of OX2R with respect to other leukocyte IgSF glycoproteins suggests that OXR2 and OX2 share a common ancestral protein.
The cytoplasmic portion of OX2R contains NPXY motifs that are known to interact with PTB/PID binding domains.
The interaction between OX2 and OX2R may contribute to pathways that suppress and limit macrophage induced inflammatory damage in tissue.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.3, 0.05% sodium azide.
Specificity：Recognizes endogenous levels of human CD200R1 protein. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to aa250-300 of human CD200R1.
