84-5127-55　［取扱停止］ABCF1 100ul　505541

特徴

• ABCF1 (ATP-binding cassette sub-family F member 1, TNF-alpha-stimulated ABC protein) is a 845aa protein encoded by the human gene ABCF1.
• ABCF1 belongs to the ABC transporter family (EF3 subfamily) and contains two ABC transporter domains.
• ABC proteins transport various molecules across extra- and intra-cellular membranes.
• ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).
• Unlike other members of the superfamily, this protein lacks the transmembrane domains which are characteristic of most ABC transporters.
• ABCF1 is believed to have a role in mRNA translation due to its interaction with eukaryotic initiation factor 2 (eIF2).
• It is also associated with ribosomes.
• ABCF1 is ubiquitously expressed and can be induced with TNF.
• Upon DNA damage, ABCF1 is phosphorylated by either ATM or ATR.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.