84-5127-34　［受注停止］High Mobility Group Box Protein 3 (HMGB3) [KO Validated] 200ul　502722

特徴

• HMGB3, also known as High mobility group protein B3, is a DNA associated protein that binds preferentially single-stranded DNA and unwinds double stranded DNA.
• This transcription factor belongs to the HMGB family and high mobility group (HMG) protein superfamily and contains two HMG box DNA-binding domains.
• Like other members of the family, HMGB3 plays a fundamental role in DNA replication, nucleosome assembly and transcription.
• Other functions include regulation of balance between hematopoietic stem cell self-renewal and differentiation and may also be required during embryonic development.
• HMGB3 is predominantly expressed in placenta.
• Applications:Suitable for use in Immunoprecipitation, Western Blot, Immunohistochemistry and Immunocytochemistry.
• Other applications not tested.
• Recommended Dilutions:Western Blot: 0.5-2ug/mlImmunohistochemistry (frozen/paraffin): 5-20ug/mlImmunocytochemistry: 5-20ug/mlOptimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.