Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum.
It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits.
It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins.
Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation.
Additionally it may play a role in receptor- mediated endocytosis at the synapse.
Applications:Suitable for use in Indirect Flow Cytometry, ELISA, Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Indirect Flow Cytometry: 1:25Western Blot: 1:2000Immunohistochemistry (Paraffin): 1:25Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein A and peptide affinity chromatography.
Form:Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:Recognizes human CANX. Species Crossreactivity: mouse and rat.
Isotype:IgG
Calc Applications Abbrev:E FC IHC WB
Calc Crossreactivity:Hu Mo Rt
Immunogen:KLH conjugated synthetic peptide between 560-592 amino acids from human CANX Species sequence homology: mouse, rat.