84-5124-97 MLL3, CT 50ul 502021
特徴
- Histone methyltransferase.
- Methylates 'Lys-4' of histone H3.
- H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation.
- Central component of the MLL2/3 complex, a coactivator complex of nuclear receptors, involved in transcriptional coactivation.
- KMT2C/MLL3 may be a catalytic subunit of this complex.
- May be involved in leukemogenesis and developmental disorder.
- Applications:Suitable for use in ELISA, Immunohistochemistry.
- Other applications not tested.
- Recommended Dilution:Immunohistochemistry (Paraffin): 1:25Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：50ul
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by Protein A and peptide affinity chromatography.
- Form：Supplied as a liquid in PBS, 0.09% sodium azide.
- Specificity：Recognizes human MLL3.
- Isotype：IgG
- Calc Applications Abbrev：E IHC
- Calc Crossreactivity：Hu
- Immunogen：KLH-conjugated synthetic peptide mapping to a fragment of residues within 3784-3818 amino acids from the C-terminal region of human MLL3.
- Shelf Life：1year
- Swiss Prot Number：Q8NEZ4
- EU Commodity Code：30021010
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