May play a role in RNA metabolism in both nuclei and mitochondria.
In the nucleus binds to HNRPA1-associated poly(A) mRNAs and is part of nmRNP complexes at late stages of mRNA maturation which are possibly associated with nuclear mRNA export.
May bind mature mRNA in the nucleus outer membrane.
In mitochondria binds to poly(A) mRNA.
Plays a role in translation or stability of mitochondrially encoded cytochrome c oxidase (COX) subunits.
May be involved in transcription regulation.
Cooperates with PPARGC1A to regulate certain mitochondrially encoded genes and gluconeogenic genes and may regulate docking of PPARGC1A to transcription factors.
Seems to be involved in the transcription regulation of the multidrug-related genes MDR1 and MVP.
Part of a nuclear factor that binds to the invMED1 element of MDR1 and MVP gene promoters.
Binds single-stranded DNA (By similarity).
Applications:Suitable for use in ELISA, Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:2000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A and peptide affinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity：Recognizes human LRPPRC. Species Crossreactivity: mouse.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu Mo
Immunogen：KLH-conjugated synthetic peptide mapping to a fragment of residues within aa847-876 of the Central region of human LRPPRC.
