Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state.
In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization.
Augments the production of reactive oxygen species (ROS) by NADPH oxidase.
Applications:Suitable for use in Immunofluorescence, ELISA, Western Blot.
Other applications not tested.
Recommended Dilution:Immunofluorescence: 1:25Western Blot: 1:2000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein A and peptide affinity chromatography.
Form:Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:Recognizes human RAC2. Species Crossreactivity: mouse.
Isotype:IgG
Calc Applications Abbrev:E IF WB
Calc Crossreactivity:Hu Mo
Immunogen:KLH-conjugated synthetic peptide mapping to a fragment of residues within aa178-192 of the C-terminal region of human RAC2.