Active metalloproteinase with gelatinolytic and collagenolytic activity.
Plays a role in the wound healing process.
Mediates both heterotypic intraepithelial cell/T-cell interactions and homotypic T-cell aggregation.
Inhibits beta-1 integrin-mediated cell adhesion and migration of airway smooth muscle cells.
Suppresses cell motility on or towards fibronectin possibly by driving alpha-v/beta-1 integrin (ITAGV-ITGB1) cell surface expression via ERK1/2 inactivation.
Cleaves E-cadherin in response to growth factor deprivation.
Plays a role in glomerular cell migration.
Plays a role in pathological neovascularization.
May play a role in cartilage remodeling.
May be proteolytically processed, during sperm epididymal maturation and the acrosome reaction.
May play a role in sperm-egg binding through its disintegrin domain.
Applications:Suitable for use in ELISA, Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:2000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A and peptide affinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity：Recognizes human ADAM15.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：KLH-conjugated synthetic peptide mapping to a fragment of residues within aa37-72 of human ADAM15.
