Regulatory component of the SET1 complex implicated in the tethering of this complex to transcriptional start sites of active genes.
Facilitates histone H3 'Lys-4' methylation via recruitment of the SETD1A or SETD1B to the 'Ser-5' phosphorylated C-terminal domain (CTD) of RNA polymerase II large subunit (POLR2A).
Component of PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.
Applications:Suitable for use in Indirect Flow Cytometry, ELISA, Western Blot.
Other applications not tested.
Recommended Dilution:Indirect Flow Cytometry: 1:25Western Blot: 1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A and peptide affinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity：Recognizes human WDR82. Species Crossreactivity: mouse, zebrafish.
Isotype：IgG
Calc Applications Abbrev：E FC WB
Calc Crossreactivity：Hu Mo Ze
Immunogen：KLH-conjugated synthetic peptide mapping to a fragment of residues within aa50-85 of the N-terminal region of human WDR82. Species sequence homology: xenopus, chicken.
