84-5117-57 HUMAN-CTNND1_isform 2ABC (Y174) 200ul 501840
特徴
- Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity).
- Associates with and regulates the cell adhesion properties of both C-, E- and N-cadherins, being critical for their surface stability.
- Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors.
- Promotes GLIS2 C-terminal cleavage.
- Applications:Suitable for use in ELISA, Western Blot.
- Other applications not tested.
- Recommended Dilution:Western Blot: 1:2000Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：200ul
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by Protein A and peptide affinity chromatography.
- Form：Supplied as a liquid in PBS, 0.09% sodium azide.
- Specificity：Recognizes human HUMAN-CTNND1_isform 2ABC.
- Isotype：IgG
- Calc Applications Abbrev：E WB
- Calc Crossreactivity：Hu
- Immunogen：KLH-conjugated synthetic peptide mapping to a fragment of residues within aa160-200 of human HUMAN-CTNND1_isform 2ABC.
- Shelf Life：1year
- Swiss Prot Number：O60716
- EU Commodity Code：30021010
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