Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids.
Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase.
It therefore controls the peroxisomal beta-oxidation pathway of fatty acids.
Key regulator of adipocyte differentiation and glucose homeostasis.
ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer.
Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated proinflammatory responses.
Applications:Suitable for use in ELISA, Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A and peptide affinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity：Recognizes human PPARG. Species Crossreactivity: mouse.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu Mo
Immunogen：KLH-conjugated synthetic peptide mapping to a fragment of residues within aa2-35 of the N-terminal region of human PPARG.
